The effects of alcohol account for one in three emergency room visits every year. This is due in part to the effects of alcohol detox and withdrawal. Alcohol withdrawal is the body and brain chemistry readjusting to a permanent sober state, once the individual is no longer consuming alcohol. Chronic alcohol use changes brain chemistry by inhibiting neurotransmitters that induce feelings of relaxation and excitability. Without alcohol these neurotransmitters work in overdrive, similar to a rebound effect.